lecture 4-19 immune sys II

lecture 4-19 immune sys II - Chapter 43 continued Learning...

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Chapter 43 – continued Learning objectives: • Recognize two essential characteristics that make acquired immunity different from innate immunity. . • Describe what epitopes are. . • Explain the nature of “B” cells: Origin, unique immunological features, roles, and basis for specificity… • Learn the process of ‘clonal selection’ of a lymphocyte • Explain the difference between primary and secondary immune reponses. . • Know the function of MHC (major histocompatibility complex) proteins. . • Compose a concept map or diagram to illustrate relationships of acquired immunity components. .
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Review: Acquired vs Innate Immunity Innate nonspecific immunity Acquired very specific immunity Innate developed before “exposure” Acquired develops after exposure Acquired immunity has three important attributes: distinguishes ‘self’ from ‘non-self’ maintains ‘memory’ of antigens involves the activity of lymphocytes
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Acquired immunitiy involves humoral and cell-mediated immune responses These defend against different types of threats The humoral immune response involves the activation and clonal selection of B cells , resulting in the production of secreted antibodies The cell-mediated immune response involves the activation and clonal selection of cytotoxic T cells
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Focus for today Review
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Newly formed lymphocytes are all alike… but they later develop into B cells or T cells, depending on where they continue their maturation Figure 43.10 Bone marrow Lymphoid stem cell B cell Circulate in blood, & lymph, and concentrate in spleen, lymph nodes and lymphoid tissues T cell Thymus
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Review – continued… An antigen is any foreign molecule that is specifically recognized by
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lecture 4-19 immune sys II - Chapter 43 continued Learning...

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