ALMOTRIP TRAINING - Copy.pptx - ALM TRIP REVOLUTION TRAINING CONTENT MIGRAINE CLINICAL BACKGROUND MIGRAINE TRAETMANT MIGRAINE MARKET IN EGYPT ALM TRIP

ALMOTRIP TRAINING - Copy.pptx - ALM TRIP REVOLUTION...

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ALM TRIP* REVOLUTION
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TRAINING CONTENT MIGRAINE CLINICAL BACKGROUND MIGRAINE TRAETMANT MIGRAINE MARKET IN EGYPT
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ALM TRIP* PHARMAKOKINETICS PHARMACODYNAMICS FEATURES/BENEFITS CLINICAL TRIALS MARKET CAMPAIGN
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ALM TRIP* WORKSHOP
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MIGRAINE CLINICAL BACKGROUND
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Migraine - Definition “Migraine is a familial disorder characterized by recurrent attacks of headache widely variable in intensity, frequency and duration. Attacks are commonly unilateral and are usually associated with anorexia, nausea and vomiting” - World Federation of Neurology ALM TRIP*
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Migraine Facts Migraine is one of the common causes of recurrent headaches According to IHS, migraine constitutes 16% of primary headaches Migraine afflicts 10-20% of the general population More than 2/3 of migraine sufferers either have never consulted a doctor or have stopped doing so Migraine is underdiagnosed and undertreated Migraine greatly affects quality of life. The WHO ranks migraine among the world’s most disabling medical illnesses ALM TRIP*
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Migraine Facts Problematic 40% UK pop Migraine occurs in 12-15% UK pop Estimated 187,000 attacks daily 75% report disability at least sometimes 90,000 absenteeism work / school daily Lost work / impaired effectiveness £1.5 bill. per year ALM TRIP*
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Burden Of Migraine World - 15-20% of women and 10-15% of men suffer from migraine In India, 15-20% of people suffer from migraine Adults – Female: Male ratio is 2 : 1 In childhood migraine, boys and girls are affected equally until puberty, when the predominance shifts to girls. ALM TRIP* NEJM 2002; 346(4): 257-269; XI Congress of the IHS, 2004
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MIGRAINE TRIGGERS
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Migraine Triggers Food Disturbed sleep pattern Hormonal changes Drugs Physical exertion Visual stimuli Auditory stimuli Olfactory stimuli Weather changes Hunger Psychological factors ALM TRIP*
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Phases of Acute Migraine 1. Prodrome 2. Aura 3. Headache 4. Postdrome ALM TRIP*
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PRODROME Vague premonitory symptoms that begin from 12 to 36 hours before the aura and headache Symptoms include Yawning Excitation Depression Lethargy Craving or distaste for various foods Duration – 15 to 20 min ALM TRIP*
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AURA Aura is a warning or signal before onset of headache Symptoms Flashing of lights Zigzag lines Difficulty in focusing Duration : 15-30 min ALM TRIP*
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HEADACHE Headache is generally unilateral and is associated with symptoms like: Anorexia Nausea Vomiting Photophobia Phonophobia Tinnitus Duration : 4-72 hrs ALM TRIP*
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POSTDROME (RESOLUTION PHASE) Following headache, patient complains of Fatigue Depression Severe exhaustion Some patients feel unusually fresh Duration: Few hours or up to 2 days ALM TRIP*
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MIGRAINE – CLASSIFICATION According to Headache Classification Committee of the International Headache Society, Migraine has been classified as: Migraine without aura (common migraine) Migraine with aura (classic migraine) Complicated migraine ALM TRIP*
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Migraine Without Aura
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