4.27 Herbal Drugs Steroids_04-27-2017.pptx

4.27 Herbal Drugs Steroids_04-27-2017.pptx - Societal Issue...

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Societal Issue: Herbal Drugs and Steroids Buzzed Chapter 5 (Herbal Drugs) + Chapter 11 (Steroids)
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Today We’ll Cover Herbal drugs St. John’s Wort Melatonin Anabolic Steroids
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Herbal Drugs AKA supplements Drugs from plant matter Definition: An herb (also called a botanical ) is a plant or plant part used for its scent, flavor, and/or therapeutic properties Can cause health problems
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Just because it says “Natural” DOES NOT equal “SAFE” CAN cause medical problems if used incorrectly Some people WILL experience negative effects even when taken correctly Powerful drugs ARE extracted from plants Examples: Cocaine, Opium, Tobacco Natural Better
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Herbal Drugs, Cont. NOT regulated by FDA as drugs In US, herbal/other dietary supplements regulated by FDA as foods NOT scheduled by DEA Does NOT have to meet the same standards as drugs o OTC meds
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Dietary Supplement Health & Education Act Dietary supplements with “established ingredients” may be marketed without any evidence of efficacy or safety For new ingredients manufacturers must provide evidence supporting a “reasonable expectation of safety” However, this has not been enforced.
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Dietary Supplement Health & Education Act Since became law, number of available supplements skyrocketed From estimated 4,000 to more than 55,000 Not known how many new supplements include novel (post-1994) ingredients FDA has received adequate notification for only 170 new supplement
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Dietary Supplement Health & Education Act, Cont. New guidelines proposed for assessing new ingredients scientific evidence for purpose of improving safety Would require in vitro, animal, and tolerability testing for consumption at doses greater than those historically ingested *Peter Cohen “Assessing Supplement Safety” New England Journal of Medicine 2012;366:389-391 Safety of supplements evaluated based on: Documented history of use Formulation Proposed daily dose Recommended duration of use Any ingredient prepared/formulated in novel manner considered “new ingredient” Will create database of evidence for making informed decisions about use of supplements
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Herbal Drug Audio/Video What is really in herbal supplements? PBS NewsHour John Oliver’s take….
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St. John’s Wort Historically used to treat: Mental health disorders; Nerve pain; Malaria; As sedative; As balm for wounds, Burns & insect bites Today used as traditional remedy for: Depression; Anxiety; Sleep disorders
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St. John’s Wort,
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