Actin Cytoskeleton as a Virulence Target in Gene-for-Gene Resistance

Actin Cytoskeleton as a Virulence Target in Gene-for-Gene Resistance

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“The NDR1- Actin Connection: The Actin Cytoskeleton as a Virulence Target in Gene-for-Gene Resistance” The molecular basis of plant-pathogen interactions are resistance (at the cellular level) and susceptibility. The role of actin in plant defense signaling was studied. The effectors and actin were studied because it provides a model for studying virulence strategies of pathogenic bacteria. The NDR1 Actin Connection is the host defenses, gene for gene and the integrin- fibrogenetics. The pseudomonas syringae infection of the Arabidopsis was the infection studied. During an infection the pseudomonas syringae remains extracellular. The pathogen communicates with plant cells via type III secretion system. It was discovered that the type III secretion injects effector proteins which ends up shutting down the basic functions of plants.
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Unformatted text preview: Thus, this leads to a rise in R-proteins which recognize the effectors activity. It was demonstrated that the ADF4 is required for hypersensitive response (cell death). The activation of resistance in the plants involves hormones, lipids, physical barriers, chaperones, vesicular trafficking, and cell wall modifications. The primary features of innate immunity in plants and animals were compared. In plants there is no mobile cell and no specialized immune cells whereas in animals the cells are mobile and the cells have a specialized surveillance system. In plants the cells have no adaptive immunity whereas animals have an adaptive immunity. Plants use 5-12% of their free pole of actin, whereas animals use 90% of their free pole of actin....
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This essay was uploaded on 03/19/2008 for the course LBS 144 taught by Professor Urquhart/peters during the Spring '07 term at Michigan State University.

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