36_Lieb_Reverse_Genetics

36_Lieb_Reverse_Genetics - Reverse Genetics J. Lieb Mouse...

Info iconThis preview shows pages 1–5. Sign up to view the full content.

View Full Document Right Arrow Icon
Reverse  Genetics J. Lieb Wild-type Bmp7 -/- Mouse Embryos
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Review of Last Lecture  "Model" Organisms in Biology What allows us to use them? 1.  All organisms share similar cellular machinery 1. All animals use this machinery in similar ways to direct embryonic development Why use them? Perform controlled experiments on a large number of samples to learn about: Basic Molecular Mechanisms (Yeast Cell Cycle: Cancer) Mechanisms of Genetics (Mendel’s Peas; Fruit Flies) Embryonic Development ( C. elegans , Sea Urchins; Mice) What does one look for when choosing a model? Fast, cheap, easy to observe and manipulate, and has the feature you want to study C. elegans , Flies. ..
Background image of page 2
The mouse provides a superb model for human development and disease because we share virtually ALL of our genes and use them in similar ways Other Models:  E. coli , Yeast, Neurospora, Arabidopsis
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Transgenics Using the power of molecular biology to isolate and  clone the DNA of our choice, and then to express
Background image of page 4
Image of page 5
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 30

36_Lieb_Reverse_Genetics - Reverse Genetics J. Lieb Mouse...

This preview shows document pages 1 - 5. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online