lecture_19_Evolutionof_genes_genomes_SW

lecture_19_Evolutionof_genes_genomes_SW - - oth speciation...

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-Both speciation and extinction increase with latitude -Implies that higher richness in tropics is due to lower extinction -NOTE: HIGHER SPECIATION RATE DOES NOT MEAN MORE SPECIES IN TEMPERATE REGIONS
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Understanding the Evolutionary Process 1) Microevolutionary processes 2) Speciation 3) Diversification (rates and patterns of speciation and extinction) 4) genetic mechanisms
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Evolution of Genes and Genomes: Linking Organismal Evolution with changes in DNA
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Evolution of Genes and Genomes -how and why do genes and genomes evolve? -how do genetic changes lead to phenotypic evolution? -does evolution proceed via many mutations of tiny effect, or fewer mutations of large effect? -does evolutionary change typically involve changes in gene regulation or gene structure? -how many genes are subject to adaptive evolution? -how does novelty and complexity arise?
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Genome Evolution 1) patterns of similarity and differences Human Mouse
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The Neutral Theory: The Simplest Explana6on M. Kimura (1924-1974)
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Molecular Evolu6on Under the Neutral Theory: Explaining Varia6on in levels of diversity and rates of Evolu6on •Strongly deleterious mutations have a very low probability of getting fixed or being polymorphic and are ignored •regions of the genome/genes with a higher F o will have higher rates of evolution •regions of the genome/genes that are more CONSTRAINED
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lecture_19_Evolutionof_genes_genomes_SW - - oth speciation...

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