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Unformatted text preview: N NO CH 3 NH 2 O N-methylnitrosourea ether H 2 C N N Generation of diazomethane KOH, H 2 O, 0°C Chapter 23 Reactions -continued R N C O R'OH R N O R' H O Reaction of isocyanate with alcohols to form urethanes R NH 2 O Br 2 , HO — H 2 O, ! R—NH 2 Hofmann Rearrangement R Br R N 3 R NH 2 Reduction of azides to form primary amines NaN 3 H 2 , Pd/C R Cl O 1. NaN 3 , ! 2. H 2 O RNH 2 Curtius Rearrangement to form primary amines R Cl O N 3 — R N O N N .. .. heat R N C O + N 2 Curtius Rearrangement R N C O H 2 O RNH 2 + CO 2 R N C O R'NH 2 R N N R' H O Reaction of isocyanate with amines to form ureas H R NH 2 O R N O Br .. .. heat R N C O + Br — Hofmann Rearrangement OBr...
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This note was uploaded on 04/22/2009 for the course CHEM 3570 taught by Professor Ganem, b during the Fall '06 term at Cornell.
- Fall '06
- GANEM, B