This preview shows page 1. Sign up to view the full content.
Unformatted text preview: Alcohols to Aldehydes: Collins Reagent R OH Na 2 Cr 2 O 7 aq. H 2 SO 4 R OH O Oxidation of Primary Alcohols to Carboxylic Acids: Cr(VI) reagents in aqueous acid. Can also use permanganate in basic solution. Na 2 Cr 2 O 7 aq. H 2 SO 4 R OH R R O R Oxidation of Secondary Alcohols to Ketones: Using dichromate. Can also use PCC, Collins Reagent; Cr(VI) reagents in aqueous acid or permanganate in basic solution. R OH SOCl 2 R Cl R R Conversion of Alcohols to Halides R OH PX 3 R X R R Conversion of Alcohols to Halides O H 2 C CH 2 RMgBr + then H 3 O + RCH 2C H 2 OH Addition of Organomettalic Reagents to Epoxides H 3 O + RMgBr RH Protonolysis of Grignard Reagents...
View Full Document
- Fall '08