Lec8_07 - permeabilities, potentials and threshold. 5....

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Lec8.htm 2007 INTRODUCTORY ANIMAL PHYSIOLOGY BIOAP 311/VETBM 346 FALL 2007 OUTLINE - LECTURE 8 Action Potentials (Readings - Chapter 3 to page 37) I. Major Topics/Concepts to be covered: 1. Action potentials. 2. Threshold and excitability. 3. Refractory periods. 4. The sodium hypothesis. 5. Voltage gated channels. 6. The Hodgkin cycle. 7. Ionic basis of the total action potential. II. You will have learned the material when you can: 1. Explain the waveforms of the transmembrane potentials measured to stimuli below and above threshold. 2. Understand the relationships between membrane potential, excitability and threshold. 3. List the steps involved in the generation of an action potential with respect to permeability and ion flow changes. 4. Explain absolute and relative refractory periods in terms of
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Unformatted text preview: permeabilities, potentials and threshold. 5. Understand the basis for regenerative sodium entry into the cell when threshold is reached. 6. Explain the roles of sodium and potassium in producing the waveform of the action potential. III. Sample Problems: 1. How might extracellular Ca++ increase the excitability of a nerve cell? 2. How will decreasing the extracellular K+ affect the waveform of the action potential and the duration of the relative refractory period? 3. Does moving the threshold closer to the resting potential make a cell more or less excitable? Explain your answer. file:///C|/WINWORD/COURSES/31107/Lec8-07.HTM8/15/2007 10:16:55 AM...
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This note was uploaded on 04/22/2009 for the course BIO 311 taught by Professor Baustian during the Fall '08 term at Cornell University (Engineering School).

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