Lec10_07 - 4. Explain how synapses can be either excitatory...

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Lec10 - 2007 INTRODUCTORY ANIMAL PHYSIOLOGY BIOAP 311/VETBM 346 FALL 2007 OUTLINE - LECTURE 10 Synaptic Transmission (Readings - Chapter 4) I. Major Topics/Concepts to be covered: 1. Terminology of synaptic contacts. 2. Electrical vs. chemical transmission at synapses. 3. Rectifying vs. non-rectifying synapses. 4. Morphology of chemical synapses. 5. Pre- and post-synaptic cell electrical responses. 6. Excitatory and inhibitory synapses. 7. Properties of synaptic junctions. 8. Cholinergic and adrenergic synapses. 9. Mechanisms of presynaptic transmitter release. II. You will have learned the material when you can: 1. Outline the differences between electrical and chemical synapses. 2. List the steps involved in the transmission of information across a chemical synapse from the arrival of an action potential at the presynaptic terminal to the electrical response of the postsynaptic cell. 3. List the differences between cholinergic and adrenergic synapses.
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Unformatted text preview: 4. Explain how synapses can be either excitatory or inhibitory. 5. List the factors responsible for determining the magnitude and time-course of the postsynaptic response. III. Sample Problems. 1. Can a given neuron be both excitatory and inhibitory to postsynaptic cells? 2. What effect would applying an anticholinesterase at the synaptic cleft have on a post-synaptic cell? 3. What is the evidence for the quantal release of transmitter? 4. What is the role of Ca++ in the process of synaptic transmission and how can the amount of transmitter file:///C|/WINWORD/COURSES/31107/Lec10-07.htm (1 of 2)8/15/2007 10:16:56 AM Lec10 - 2007 released/action potential be regulated? 5. Define summation of synaptic activity in terms of ion flow and transmitter release. 6. What determines whether a synapse is excitatory or inhibitory? file:///C|/WINWORD/COURSES/31107/Lec10-07.htm (2 of 2)8/15/2007 10:16:56 AM...
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Lec10_07 - 4. Explain how synapses can be either excitatory...

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