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Lec29_07 - how this carrying capacity is affected by...

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Lec29-2007 INTRODUCTORY ANIMAL PHYSIOLOGY BIOAP 311/VETBM 346 FALL 2007 OUTLINE - LECTURE 29 Gas Transport (Readings - Chapters 30) I. Major Topics/Concepts to be covered: 1. Gas exchange in the lungs and tissues. 2. Gas solubility and the need for Hemoglobin 3. Oxygen transport. 4. Oxygen-Hemoglobin dissociation curves and the factors affecting them. 5. Carbon dioxide transport - Figure 30-8. 6. The Haldane effect. II. You will have learned the material when you can: 1. Draw and use the gas gradients in the lungs and tissues to explain the diffusion of gases. 2. Read oxygen dissociation curves and predict how they will be affected under different metabolic conditions (e.g. understand the Bohr shift). 3. List the ways in which carbon dioxide is carried in the blood and
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Unformatted text preview: how this carrying capacity is affected by various conditions such as pH and oxygen binding to hemoglobin. III. Sample Problems: 1. If the affinity of hemoglobin for oxygen increases, which way does this move the oxygen dissociation curve - right or left? 2. What effect does increasing the pH have on oxygen dissociation and why is this adaptive? 3. What effect would blocking RBC carbonic anhydrase have on carbon dioxide carrying capacity and what is the underlying physiology explaining your answer? 4. What would the oxygen dissociation curve look like for a molecule having a single oxygen binding site? file:///C|/WINWORD/COURSES/31107/Lec29-07.htm8/15/2007 10:24:08 AM...
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