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Lec35_07 - osmolarity 3 Understand how the vasa recta works...

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Lec35 - 2007 INTRODUCTORY ANIMAL PHYSIOLOGY BIOAP 311/VETBM 346 FALL 2007 OUTLINE - LECTURE 35 Dilute and Concentrated Urine Production (Readings - Chapter 38) I. Major Topics/Concepts to be covered: 1. ADH and the regulation of urine concentration. 2. Osmotic gradients along the nephron. 3. Permeabilities along the nephron. 4. The countercurrent multiplier of the Loop of Henle. 5. The countercurrent exchange mechanism of the vasa recta. 6. Regulation of the E xtra C ellular F luid Volume II. You will have learned the material when you can: 1. Explain how ADH regulates urine concentration. 2. Understand how the countercurrent multiplier increases the medullary
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Unformatted text preview: osmolarity. 3. Understand how the vasa recta works to prevent washout of the medullary osmolytes. 4. Outline the regulatory pathways controlling the ECF volume. III. Sample Problems: 1. How does an increase in ADH lead to the retention of water? 2. What is the main energy source for establishing the osmotic gradient between the medulla and cortex? 3. How would a decrease in GFR affect the magnitude of the osmotic gradient in the medulla? 4. Why do uncontrolled diabetics produce large volumes of dilute urine? 5. What is diabetes insipidus? file:///C|/WINWORD/COURSES/31107/Lec35-07.htm8/15/2007 10:26:55 AM...
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