Lecture Review 5 - BIO311C (2008) Introductory Biology I...

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BIO311C (2008) Introductory Biology I Lecture Review 04 (02/15-02/18) Cytoskeleton, membrane 1. Cytoskeleton (1) Functions of structure and movement of cells require three types of protein filaments and associated proteins a. Mechanical support – maintain the shape of the cell b. Dynamic structure – quickly dissembled and reassembled c. Motility – e.g. transport vesicles from ER through Golgi to plasma membrane (2) Three types of cytoskeleton are made by small subunits a. Microtubules : smaller, globular subunits b. Microfilaments : smaller, globular subunits c. Intermediate filaments : elongated subunits (3) Motor proteins move or travel along filaments uni-directionally by using energy from ATP hydrolysis . (4) Microtubules (MT) Æ Subunit is a heterodimer : α -tubulin+ β -tubulin Æ Diameter: 25 nm Æ MT is a hollow tube (stronger structure) Æ Main functions of microtubules: a. support (shape) b. movement within cell – e.g. chromosomes, organelles, vesicles c. movement of entire cell -- Cilia and Flagella Æ Centrosome - organizing centers for microtubules 1
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Lecture Review 5 - BIO311C (2008) Introductory Biology I...

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