2016.GI System Glands Blackboard.ppt

2016.GI System Glands Blackboard.ppt - Digestive System...

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Unformatted text preview: Digestive System Glands VI. Pancreas A. General features 1. 2. Stroma - loose CT Parenchyma a. b. endocrine gland exocrine gland B. Endocrine pancreas 1. 2. 3. 4. Islets of Langerhans Beta cells Alpha cells Delta cells B. Endocrine pancreas 1. 2. 3. 4. Islets of Langerhans Beta cells Alpha cells Delta cells Pancreas C. Exocrine pancreas C. Exocrine pancreas 1. Acini - the main functional units a. b. c. organization and polarity secretory products cholecystokinin Pancreatic Acinar Cell C. Exocrine pancreas 2. Ducts a. b. c. d. e. f. secretory canaliculi centroacinar cells intercalated ducts interlobular ducts excretory ducts duodenum C. Exocrine pancreas 2. Ducts a. b. c. d. e. f. secretory canaliculi centroacinar cells intercalated ducts interlobular ducts excretory ducts duodenum C. Exocrine pancreas 2. Ducts a. b. c. d. e. f. secretory canaliculi centroacinar cells intercalated ducts interlobular ducts excretory ducts duodenum Digestive System VII. Liver A. General features • • • largest gland, approximately 1500 g receives a large volume of blood via portal vein and hepatic artery metabolizes products of digestion, stores glucose, detoxifies A. General features 1. exocrine & endocrine gland a. b. 2. bile plasma proteins structural plan a. b. c. cellular plates & central vein hepatocytes & sinusoids stroma & lobules B. Lobulation 1. 2. 3. Basic lobule CT Blood flow C. Lobulation patterns 1. Classical hepatic lobule a. b. c. anatomical limits a hexagon blood flow C. Lobulation patterns 2. Portal lobule a. b. c. anatomical limits a triangle bile flow C. Lobulation patterns 3. Liver acinus a. b. no anatomical limits diamond-shaped D. Portal canal 1. 2. 3. 4. Hepatic artery Portal vein Bile duct Lymphatic channels Portal Canal E. Hepatocytes 1. Intercellular relationships a. b. c. space of Disse bile canaliculi cell junctions Space of Disse E. Hepatocytes 2. Cytoplasm a. b. c. d. 3. RER and polysomes smooth ER mitochondria organelles Nucleus Hepatocyte Protein Synthesis & Glucose Bile Secretion F. Hepatic sinusoids 1. Endothelium F. Hepatic sinusoids 2. Hepatic sinusoids – zonation pattern Tylenol Poisoning F. Hepatic sinusoids 3. Kupffer cells F. Hepatic sinusoids 3. Kupffer cells F. Hepatic sinusoids 3. Kupffer cells F. Hepatic sinusoids 4. Central veins G. Bile passages 1. 2. Bile canaliculi Intrahepatic bile ducts a. b. 3. canals of Hering ducts of portal canals Hepatic duct G. Bile passages 1. 2. Bile canaliculi Intrahepatic bile ducts a. b. 3. canals of Hering ducts of portal canals Hepatic duct Digestive System VIII. Gall Bladder A. General features and functions 1. 2. Anatomic divisions Peritoneum 3. Functions a. b. store & concentrate bile bile emulsifies fat Gall Bladder B. Epithelium 1. 2. Pseudodiverticulae Surface cells Gallbladder Gall Stones ...
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