NUR 226 QUIZ #8 Integumentary.docx - Name Definition Etiology S\/S Contact Dermatitis Inflammatory skin disorder d\/t direct exposure-direct chemical or

NUR 226 QUIZ #8 Integumentary.docx - Name Definition...

This preview shows page 1 - 3 out of 6 pages.

Name DefinitionEtiology S/SDiagnosis and TreatmentContact Dermatitis Inflammatory skin disorder d/t direct exposure-direct chemical or mechanicalirritation -does not involve immune responseHypersensitivity response to allergen:-metals, cosmetics, soaps,chemicals, plants-sensitization occurs on 1st exposure-pruritic rash develops at site a few hours after exposure-type IV allergic rxns-cell mediatedPain, redness, pruritusTX:-removal of irritant-reduction of inflammation w/topical glucocorticoidAtopic Dermatitis (Eczema)Chronic w/ exacerbations -genetic predisposition-type I hypersensitivity rxn (allergy rxn)Skin scaly, dry, leathery, raw, reddenedTX: symptomatic tx-lotions/ ointments to control itching & flaking of the skin·topical glucocorticoids most effective-relieve local inflammation & itching-adverse effects w/long term use: redness, irritation, thinning of the skin -available in creams, gels, solutions, pads-antihistamines to control inflammation & itching-analgesics/ topical anesthetics for pain-identity triggers & eliminate them Urticaria (Hives)Result of hypersensitivity I -ingestion of substances such as shellfish, drugs, certain fruits-often a part anaphylaxis Lesions are highly pruritic-check for swelling around mouth and check airway-administer EpiPen or other first aid as requiredPsoriasisHyperplasia of the epidermis-chronic inflammatory -extremely fast cell turnover rate d/t abnormal T cell activation ·excessive proliferation of keratinocytes·cellular proliferation ↑Cause: unknown, genetic & autoimmune-increased mitosis and shedding of the epithelium Red, elevated plaquesw/ silvery scales-lesions found on face,scalp, elbows, knees -itching or burning sensationsTX: to reduce erythema, plaques, scales to improve appearance-no pharmacological cure-Topical therapies:a.topical immunomodulators (TIM): suppresses immune system-protopic ointment-Calcipotriene (Dovonex)not used long term d/t hypercalcemia risk-Tazarotene (Tazarac)-same benefit as topical steroids but less side effectsb. retinoid-like compoundsc. tar tx & anthralin: inhibit DNA synthesis & arrestabnormal cell growthd. topical corticosteroids: Dexamethasone &
Background image
hydrocortisone acetate=↓inflammation associated w/fast skin turnover+high potency for 2-3 wks then ↓ med to lowPotency-Systemic therapy: used when topical ineffective· Methotrexate· Acitretin-inhibits excessive skin growth· Cyclosporine- immunosuppressive agent -Biologic agents- suppress inflammatory and immune -very expensive-Parenteral admin only· Adalimumab (Humira)· Etanercept (Enbrel)-Coal Tar application: applied to skin surface; inhibits DNA synthesis- abnormal cell growth-Phototherapy:· UVA & UVB + methoxsalen· used w/severe debilitating psoriasis· reduces lesions, unpleasant side effects· UVA alone is less hazard, can self administerScleroderma-may occur as a skin disorder-may be systemic and affect viscera-may cause renal failure, intestinal obstruction, respiratory failure d/t distortion of tissues-primary cause unknown·↑collagen deposition
Background image
Image of page 3

  • Left Quote Icon

    Student Picture

  • Left Quote Icon

    Student Picture

  • Left Quote Icon

    Student Picture