ANP LO 6.doc - LO6 Bio 241 Chapters 9 10 Learning...

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LO6 Bio 241 Chapters 9 & 10 Learning Objectives 1.What are the three different muscle tissue types? Describe where in the body each type of muscle is located, and state whether they exhibit voluntary or involuntary contractions. Type of muscle tissue Voluntary or involuntary Location Skeletal muscle tissue Striated, Voluntary walls of hollow visceral organs Cardiac muscle tissue Striated, Involuntary heart Smooth muscle tissue Not striated, involuntary Stomach, urinary bladder, and airways 2.What are the major functions of skeletal muscles? 1. produce skeletal movement 2. maintain posture and body position 3. support soft tissues 4. guard entrances exit 5. maintain body temperature 6. store nutrient reserves 2.Describe the 3 layers of connective tissues that cover muscles. Epimysium: dense regular connective tissue surrounding entire muscle Perimysium: fibrous connective tissue surrounding fascicles Endomysium: fine areolar connective tissue surrounding each muscle fiber 3.Draw and describe the microstructure of a muscle fiber. Include the following terms in your description: nuclei, sarcolemma, sarcoplasm, myofibril, T-tubules, sarcoplasmic reticulum, thin filaments and thick filament. Muscle fiber Description nuclei On the sarcolemma sarcolemma Outer membrane covering of a skeletal muscle fiber sarcoplasm Cytoplasm of the muscle fiber Myofibril bundles of very fine cytoskeletal filaments that extend lengthwise along skeletal muscle fiber and almost fill the sarcoplasm t-tubules transverse tubules, formed by inward extensions of the sarcolemma; main function is to allow electrical signals to move deeper into the cell Sarcoplasmic reticulum the muscle fiber's version of smooth endoplasmic reticulum Thin filaments actin, troponin, and tropomyosin Thick filament myosin and their heads 4.Describe the following: F actin, G actin, tropomyosin, troponin. Briefly describe how they relate to each other. 1
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Term Description F actin a fibrous actin polymerized in the form of a double helix that is produced in the presence of a metal cation (as of calcium) and ATP G actin a globular monomeric form of actin produced in solutions of low ionic concentration tropomy osin a muscle protein of the I band that inhibits contraction by blocking the interaction of actinand my osin, except when influenced by troponin. troponin a protein of muscle that together with tropomyosin forms a regulatory protein complex controlling the interaction of actin and myosin and that when combined with calcium ions permits muscular contraction The thin filaments also contain the regulatory proteins called tropomyosin and troponin, which regulate the interaction of actin and myosin. Tropomyosin serves to block the active site on actin, thereby inhibiting actin and myosin from binding under resting conditions.
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