CH369Exam2_v1_key - CH 369 Exam 2 (version 1) Feb. 14. 2008...

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CH 369 Exam 2 (version 1) Feb. 14. 2008 (Happy Valentine’s Day!!) Name: UTEID: Instructions: 1. Please bubble in your name, UTEID and the version number of your exam on the scantron sheet. 2. Answers 1-49 must be marked on the scantron sheet. Only the scantron sheet will be graded. 3. Questions 50-52 should be answered on this exam. 4. All requests for addition error or regrading must be made within 1week of receiving your exam. No exceptions. 5. Addition errors and regrading questions 50-52 should be taken to the TA. Any exam turned in for regrade will be completely regarded. Section Points I 10 II 78 III 12 Total 100
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Section I: (1pt. each) (Question 1 and 2) This is a diagram of muscle contraction. 1. A is a motor protein called kinesin a. True b. False 2. B is a microfilament called tubulin. a. True b. False (Question 3 - 5) What is the effect of each of the following treatments on the oxygen affinity of hemoglobin A in vitro . 3. Increase in pH from 7.2 to 7.4 a. Increase b. Decease 4. Increase in pCO 2 from 10 to 50 torrs a. Increase b. Decrease B
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5. Increase in [BPG] from 1 × 10 -4 M to 8 × 10 -4 M a. Increase b. Decrease
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(Question 6 and 7) Below is a graph of the energy level of a reaction. 6. The presence of enzyme catalyst lowers the value of C. a. True b. False 7. The reaction is spontaneous if A > D a. True b. False 8. Below is the reaction velocity of two different enzymes (A and B) vs. substrate concentration graph of an enzyme-catalyzed reaction. Which enzyme has a higher affinity of substrate? a. A b. B 9. When an actin filament is “treadmilling”, the net growth of the filament is increasing A B C B A D Free Reaction Reactant Product 0
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a. True b. False 10. In glycogen formation, the glucose molecules are linked by C1 and C4 linkage only a. True b. False
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Section II: (2pt. each) 11. On an actin filament (microfilament), actin monomers attach a. Only on the (+) end b. Only on the (-) end c. On both (+) and (-) end 12. In the myosin-actin reaction cycle, starting from the myosin head binding an ATP molecule, put the rest of the steps in order. 1. ADP + Pi is released 2. ATP is hydrolyzed to ADP + Pi 3. Myosin binds to actin and move further along the filament 4. Myosin lever returns to its original position 5. Another ATP binds to the myosin a. 2-3-1-4-5 b. 1-4-3-2-5 c. 2-1-3-4-5 d. 1-2-3-4-5 e. 3-2-4-1-5 13. Which statement about microtubules is correct? a. G-actins form protofilaments b. Microtubules are more flexible than microfilaments because they are hollow c. The (+) end grows faster than the (-) end d. Microtubules are made of long intertwined alpha-helices that form a rope structure 14. Which statement is TRUE about kinesin? a. The heads attach to the cargo vesicle b. Each head of the kinesin molecule bind to separate microtubules c. Kinesin carries its cargo from the (-) end of the microtubule towards the (+) end d. Kinesin easily dissociates from the microtubule; therefore, it is not highly processive 15. An enzyme catalyzes a reaction by
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a. Lowering the reactants’ energy state
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CH369Exam2_v1_key - CH 369 Exam 2 (version 1) Feb. 14. 2008...

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