CH369Exam2_v2_key - CH 369 Exam 2 (version 2) Feb. 14. 2008...

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CH 369 Exam 2 (version 2) Feb. 14. 2008 (Happy Valentine’s Day!!) Name: UTEID: Instructions: 1. Please bubble in your name, UTEID and the version number of your exam on the scantron sheet. 2. Answers 1-49 must be marked on the scantron sheet. Only the scantron sheet will be graded. 3. Questions 50-52 should be answered on this exam. 4. All requests for addition error or regrading must be made within 1week of receiving your exam. No exceptions. 5. Addition errors and regrading questions 50-52 should be taken to the TA. Any exam turned in for regrade will be completely regarded. Section Points I 10 II 78 III 12 Total 100
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Section I: (1pt. each) (Question 1 and 2) Below is a graph of the energy level of a reaction. 1. The presence of enzyme catalyst lowers the value of C. a. True b. False 2. The reaction is spontaneous if A > D a. True b. False 3. When an actin filament is “treadmilling”, the net growth of the filament is increasing a. True b. False 4. In glycogen formation, the glucose molecules are linked by C1 and C4 linkage only a. True b. False (Question 5 - 7) What is the effect of each of the following treatments on the oxygen affinity of hemoglobin A in vitro . C B A D Free Reaction Reactant Product 0
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5. Increase in pH from 7.2 to 7.4 a. Increase b. Decease 6. Increase in pCO 2 from 10 to 50 torrs a. Increase b. Decrease 7. Increase in [BPG] from 1 × 10 -4 M to 8 × 10 -4 M a. Increase b. Decrease (Question 8 and 9) This is a diagram of muscle contraction. 8. A is a motor protein called kinesin a. True b. False 9. B is a microfilament called tubulin. a. True b. False 10. Below is the reaction velocity of two different enzymes (A and B) vs. substrate concentration graph of an enzyme-catalyzed reaction. A B
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Which enzyme has a higher affinity of substrate? a. A b. B A B
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(2pt. each) 11. The importance of rapid turnover of microfilaments in cell motility is highlighted by the action of compound “X” from a highly poisonous mushroom. Which of the following could be mechanism(s) for the action of “X” which interferes with microfilament function, in principle? a. “X” could block the assembly of microfilaments by capping the (+) end. b. “X” could sever already formed microfilaments. c. “X” could prevent the disassembly of microfilaments. d. All of the above could be reasonable. e. All of the above could be unreasonable. 12. Which statement is TRUE during contraction? a. Myosin is GTP bound b. Myosin operates through a lever mechanism c. Myosin is a motor protein sliding across microtubule d. Myosin is a very processive motor protein 13. The erythrocytes of birds and turtles contain a regulatory molecule different from 2,3- bisphosphoglycerate (BPG). This substance is also effective in reducing the oxygen affinity of human hemoglobin stripped of BPG. Which of the following substances would you predict to be most effective in this regard? a.
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CH369Exam2_v2_key - CH 369 Exam 2 (version 2) Feb. 14. 2008...

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