Lecture5_Enzymes.pptx - Chapter 8 Energy and Enzymes An...

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Chapter 8 Energy and Enzymes: An Introduction to Metabolic Pathways
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Reminders and Important Info Worksheets from snow day are due today—please put in boxes at the back. Please be sure to pick up Worksheet #1—this is due by Friday. Osmosis and diffusion worksheets are down front and separated alphabetically—you are welcome to come down and find yours if it isn’t too crowded. Key for Osmosis and diffusion worksheet is posted online First quiz is Wednesday!! Session ID: 882309
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Enzymes Today, we are going to talk about enzymes. Enzymes are proteins that are biological catalysts that help the chemical reactions needed in a cell to occur at a pace that is needed to maintain life. They can either breakdown substrates into a product or combine substrates into product.
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Enzymes Enzymes help chemical reactions occur by helping to overcome two hurdles: o 1) Reactants colliding in a precise orientation o 2) Reactants having enough kinetic energy to overcome repulsion between electrons that come in contact as a bond forms.
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Enzymes Enzymes bring substrate molecules together in a substrate binding site known as the active site . Enzymes help substrates collide in a precise orientation so that the electrons involved in the reaction can interact.
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Enzymes The active site is a cleft or cavity within the globular shape of the enzyme.
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Enzymes When reactant molecules bind to the active site, the enzyme undergoes a conformational change, called an induced fit , which helps to bring substrates together.
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Enzymes When a substrate binds, the degree of interaction between the substrate and enzyme increases and reaches a maximum when a temporary, unstable intermediate condition called the transition state is reached.
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