b355Class37.pdf - /27/17 chromosome mutation/Xchromosome...

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1 Class 37 11/27/17 chromosome mutation/X- chromosome inactivation • Announcements • Class administration • Check iLearn for suggested problems OFFICE HOURS Mondays, 2 – 4pm, HH668C Biol 572/872 Ecology, Evolution, & Conservation Biology Colloquium 2 Eliseo Parra MS Thesis presentation Evolution of deceptive vocal mimicry in a neotropical suboscine bird Tuesday, 11/28/17 HH 543, 2:10pm Romberg Tiburon Center Seminar Series 3 Laura Rogers-Bennett UC Davis Bodega Marine Lab Marine Heat Wave Impacts Bull Kelp Forest Ecosystems in Northern California Wednesday, 11/29/17 3:30 pm, Bay Conference Center Biol 871 Colloquium in Microbiology, Cell & Molecular Biology 4 Thursday, 11/30/17 SCI 210, 2:10 pm Ouma Onguka Stanford University From phosphatidylethanolamine metabolism in yeast mitochondria to active serine hydrolase's In Toxoplasma gondii lytic development SF State Biology alumnus, Johns Hopkins Ph.D., now postdoc at Stanford
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5 Figure 18-16 nondisjunction Both homologs go to same pole If this were the X chromosome, ± diplo-X ² First-division nondisjunction Second-division nondisjunction 6 Down Syndrome • Discovered in 1866 by John Langdon Down • Now known to result from trisomy 21 (47,+21) • one per 800 live births • Several characteristics associated with Down syndrome – Epicanthic fold in each eye, flat face, round head – Physical, psychomotor, and mental development affected Figure 8.3 See Figure 18-21 7 Trisomy in humans • Patau syndrome – Trisomy 13 [47,+13] – Have developmental problems, not mentally alert,
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