Parkinson’s Disease Parkinson’s disease (PD) is a movement disorder manifested by a tremor at rest, muscle rigidity, bradykinesia/akinesia, postural disturbance, dysarthria, and dysphagia (Huether & McCance, 2017). Two forms of PD have been identified. Secondary PD is reversible, unlike primary PD. Secondary PD known causes are head trauma, infection neoplasm, atherosclerosis, toxins, and drug intoxication (Huether & McCance, 2017). PD is more prevalent in men affecting 1 in 272 individuals and is the leading cause of neurologic disability in individuals older than 60 years of age (Huether & McCance, 2017). Pathophysiology Although several genes have been identified, in relation to PD, pathogenesis remains unknown (Huether & McCance, 2017). Degeneration of mono-amine-containing cell populations within the brainstem and basal ganglia have been identified (Hammer & McPhee, 2014). Furthermore, the identification of eosinophilic, cytoplasmic inclusion bodies, known as
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- Fall '17
- keisha lovence