Review of Laboratory and Diagnostic Tests.pptx

Review of Laboratory and Diagnostic Tests.pptx - REVIEW OF...

Info icon This preview shows pages 1–10. Sign up to view the full content.

REVIEW OF LABORATORY AND DIAGNOSTIC TESTS
Image of page 1

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

Importance of Laboratory and Diagnostic Tests Data from laboratory and diagnostic tests provide important information regarding: patient’s response to drug therapy patient‘s ability to metabolize and eliminate specific therapeutic agents diagnosis of disease progression and regression of disease
Image of page 2
Invasive vs. Noninvasive Tests Invasive Tests - require penetration of the skin or insertion of instruments or devices into a body orifice Examples: collection of blood (venipuncture) insertion of central venous catheter collection of cerebrospinal fluid (CSF)
Image of page 3

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

Invasive vs. Noninvasive Tests Noninvasive Tests - do not require penetration of the skin or insertion of instruments or devices into body orifices and pose little risk to the patient Examples: chest radiograph analysis of spontaneously voided urine stool occult blood analysis
Image of page 4
Factors to consider when interpreting test results: 1. Age and gender of the patient 2. Timing of the test result in relationship to drug administration 3. Concomitant drug therapy 4. Concurrent diseases 5. Organ function (e.g. renal function, liver function) 6. Test sensitivity (the proportion of true-positive results) 7. Test specificity (the proportion of true-negative results) 8. Timing of the test in relation to drug dosing or known circadian rhythms 9. Genetics (e.g. glucose-6-phosphate deficiency) 10. Fluid status (e.g. euvolemia, dehydration, fluid overload)
Image of page 5

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

"true positive" is the event that the test makes a positive prediction, and the subject has a positive result under the gold standard and a "false positive" is the event that the test makes a positive prediction, and the subject has a negative result under the gold standard "true negative" is the event that the test makes a negative prediction, and the subject has a negative result under the gold standard, and a "false negative" is the event that the test makes a negative prediction, and the subject has a positive result under the gold standard. gold standard test usually refers to a diagnostic test or benchmark that is the best available under reasonable conditions
Image of page 6
Diagnostic Procedures for General Organ Systems Angiography Biopsy Computed Tomography Doppler Echography Endoscopy Fluoroscopy Magnetic Resonance Imaging Molecular Imaging Paracentesis Plethysmography Positron Emission Tomography Radionuclide studies Single-Photon Emission Computed Tomography Standard Radiography (Plain Films, X-Ray Films) Ultrasonography
Image of page 7

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

ANGIOGRAPHY Angiography is a radiographic test used to evaluate blood vessels and the circulation. A radiopaque material is injected through a catheter Inserted in the blood vessel and images are recorded using standard radiographic techniques.
Image of page 8
BIOPSY - involves the removal and evaluation of tissue.
Image of page 9

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

Image of page 10
This is the end of the preview. Sign up to access the rest of the document.
  • Spring '17

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern