Weekly Report #11.docx

Weekly Report #11.docx - Weekly Report for 11/5-11/12 Name...

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Weekly Report for 11/5-11/12 Name: Ruchi Gupta Lab of: Professor Lenard M. Lichtenberger Lab hours this week: 10 hours total Project Title: Aspirin and Indomethacin for the Chemoprevention of Pancreatic Cancer Project Summary: Long-term usage of nonsteroidal anti-inflammatory drugs (NSAIDs) has been shown to reduce the incidence of over 20 different types of cancer, as well as reduce the metastatic spread of cancer even when taken post-diagnosis, but the mechanism by which these class of drugs achieves these antineoplastic characteristics is not clear. Thrombocytosis, or the overproduction of platelets by the body, is frequently observed in patients with metastatic cancers, suggesting the importance of platelets in tumor progression and malignancy. Our lab will be investigating if human platelets promote thegrowth of k-ras driven pancreatic cancer tissue, as well as the ability of aspirin, indomethacin, and their PC
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  • Spring '14
  • Gustin,Michael

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