Section 1 course management and intro to cell bio_p.pptx -...

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BLG311: Cell Biology F2017Dr. Costin Antonescu1
Please see D2L for details in the Course Information Sheet2* Please allow 72 hours (3 business days) for a response. BLG311 contact information*
3Online quizzes on D2L (1)Quizzes will be worth 10% of your final grade. There will be 8 quizzes total, one for each section of the courseSection 1: Introduction to Cell BiologySection 2: Visualizing CellsSection 3: Membrane structureSection 4: Membrane transport and electrical propertiesSection 5: The Cell Cycle * (self study section)Section 6: Intracellular compartments and protein sortingSection 7: Intracellular vesicular trafficSection 8: The cytoskeletonQuizzes will be available on the day that we finish each section, and the deadline for completion will be one week. Correct answers will be posted FOLLOWING the deadline.
Section 1: Introduction to Cell BiologySection 1: Introduction to Cell BiologyReference reading (5e) : Chapter 1: pgs: 1-11; 14-16; 26-30; Chapter 2: pgs: 45-54; 55-64; 106-117; Chapter 3, pgs: 125-1271.Key concepts about cells Chemical information DNA replicationTranscription and types of RNAsTranslationCellular Energy2.Prokaryotes vs. eukaryotes: what are they and their differences3.Evolution of eukaryotic cells4.Chemical composition of cellsSmall moleculesMacromolecules (types, diversity)Macromolecule TypesShape determines function5. Protein folding and structureAmino acids and polypeptides Ligand-protein interactionskinases, phosphatase and GTPases4
WHAT IS CELL BIOLOGY?The study of the cell occurs at many levels:Molecular composition and organizationSubcellular structure and organizationFunction of the individual components of the cellCell differentiation and functionCommunication between environment and cellsCell replication5What?Where?How?
TO UNDERSTAND CELLS:A modern cell biologist understands and uses:Molecular geneticsRecombinant DNA and genetic engineeringBiochemistryGenomics and proteomicsSystems biologyBioinformaticsAdvanced microscopy and imaging6
What’s a Cell?The smallest unit of life. Inside the cell:Order and structureInside the cell:Order and structureThe non-living worldPlasma membrane:Separates the living from non-living worldsNutrients,Energy, information7
Some universal properties of cellsThe __plasma membrane_____ delineates the cell and controls the exchange and communication with the non-living world that surrounds the cell.The inside of the cell is ordered or disordered? _ordered___Cells _divide__ to form two new cells: continuation of lifeThis is possible because of the genetic code stored chemically as DNAThe DNA code is faithfully replicated by __DNA polymerase___The DNA encodes discreet units of of information: __Gene___Genes are __Transcribed__ into discreet molecules: RNARNA is then _Translated___into proteins, which are the workhorses of the cell.

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