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Chapter 7 - Chapter 7 Discovered transformation mice...

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Chapter 7 Frederick Griffith Discovered transformation, mice experiment Avery, Macleod, McCarty Destroy all major chemicals to determine which one plays a role in transformation Hershey-Chase Phosphorous and Sulfur injected into phage which were then injected into E. Coli Three Key properties of DNA Faithful replication, informational content, must be able to change or mutate Basic building blocks of DNA Phosphate, sugar (deoxyribose), four nitrogenous bases Four nitrogenous bases? Adenine, guanine, thymine, cytosine Definition of a purine Double ring structure, adenine-guanine Definition of a pyrimidine Single ring structure, cytosine-thymine What composes the groups known as nucleotides? Phosphate group, deoxyribose sugar, and any of the 4 nitrogenous bases What types of chemical bonds are in DNA? Hydrogen bonding which holds the bases together, and covalent bonding between the respective elements What are Chargaff’s rules of base composition?
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