Chapter_20(1) recorded.pptx - Chapter 20 Anxiolytic and Hypnotic Agents Copyright 2013 Wolters Kluwer Health | Lippincott Williams Wilkins Types of

Chapter_20(1) recorded.pptx - Chapter 20 Anxiolytic and...

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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Chapter 20: Anxiolytic and Hypnotic Agents
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Types of Anxiolytic and Hypnotic Agents Types of Anxiolytic and Hypnotic Agents Anxiolytics Prevent feelings of tension or fear Sedatives Calm and make patients unaware of the environment Hypnotics Cause sleep Minor Tranquilizers Produce a state of tranquility in anxious patients
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Psychological States Affected by Anxiolytic and Hypnotic Drugs Psychological States Affected by Anxiolytic and Hypnotic Drugs Anxiety Feeling of tension, nervousness, apprehension, or fear involving unpleasant reactions to a stimulus Sedation Loss of awareness and reaction to environmental stimuli Hypnosis Extreme sedation resulting in further CNS depression and sleep
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Use of Anxiolytic and Hypnotic Agents Across the Life Span Use of Anxiolytic and Hypnotic Agents Across the Life Span
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Benzodiazepine: Action Benzodiazepine: Action Act in the limbic system and the RAS Make GABA more effective Causes interference with neurons firing Lower doses assist with anxiety Higher doses cause sedation and hypnosis
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Benzodiazepine: Indications Benzodiazepine: Indications Anxiety disorders Alcohol withdrawal Hyperexcitability and agitation Preoperative relief of anxiety and tension
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Benzodiazepine: Pharmacokinetics Benzodiazepine: Pharmacokinetics Well absorbed from GI tract Peak levels achieved in 30 minutes to 2 hours Lipid soluble and distributes well throughout the body Cross placenta Enter breast milk Metabolized in the liver Excretion is primarily in the urine
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Benzodiazepine: Contraindications and Cautions Benzodiazepine: Contraindications and Cautions Allergy to benzodiazepine Psychosis Acute narrow angle glaucoma Shock Coma Acute alcohol intoxication Pregnancy
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