lec8.pdf - Write a mechanism H H2SO4 What is X Write a...

Info icon This preview shows pages 1–4. Sign up to view the full content.

+ H 2 SO 4 Write a mechanism. H + + X H A B C D What is X? Write a mechanism. What is X? H + + X A B C D What is X? Write a mechanism. H H H H H H What is the key intermediate? H O SO 3 H H H O SO 3 H H O SO 3 H + + Ways we can generate the carbocation intermediate for Friedel-Crafts alkylation: + AlCl 3 + AlCl 4 - + H + + H + B: + H 2 O
Image of page 1

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

A B Which do you expect to be the major site of reaction in electrophilic aromatic substitution? Cl 2 FeCl 3 A B C D HNO 3 H 2 SO 4 Which do you expect to be the major site of reaction in electrophilic aromatic substitution? B A C HNO 3 H 2 SO 4 2,4,6-trinitrotoluene TNT Which do you expect to be the major site of reaction in electrophilic aromatic substitution? A B Cl 2 FeCl 3 The stronger activating group dominates. Activating groups usually dominate over deactivating groups. HNO 3 H 2 SO 4 Which do you expect to be the major site of reaction in electrophilic aromatic substitution? A B + 58% 42% Are the effects of the CH 3 and Cl reinforcing or opposing?
Image of page 2
OH pk a = 9.99 O O O O OH N O O O N O O O N O O pk a = 7.15
Image of page 3

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

Image of page 4
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern