TLV Manual

TLV Manual - Term Definition The minimum oxygen requirement...

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Term: The minimum oxygen requirement is... Definition: 19.5% at sea level 148 torr Term: The TLV for particulates not otherwise specified is... Definition: 3 mg/m3 for respirable particles and 10 mg/m3 for inhalants particles. Term: The BEI(A) is for which class of compounds. Definition: Acetylcholinesterase inhibitors Term: The BEI(M) is for which class of compounds? Definition: Inducers of methemoglobin. Term: The BEI(P) is for what class of compounds? Definition: PAHs
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Term: What is the meaning of the inhalant fraction and vapor (IVF)? Definition: It is used when a material exerts sufficient vapor pressure such that it may be present in both vapor and particulate phases and each can contribute significantly to the dose. This is based on the ratio of the saturated vapor conc to the TLV. The footnote is generally used for ratios of 0.1-10. Term: The IH should consider both particulate and vapor phases to assess exposures from... Definition: From spraying operations, from processes involving temperature changes that may affect the physical state of matter, and when a significant fraction of the vapor is dissolved into or adsorbed on to particles of another substance such as water soluble compounds in a high humidity environment. Term: The DSEN and RSEN designations stand for... Definition: Dermal and respiratory sensitizers, respectively. Term: Do the SEN notations imply that these are the critical effects for the TLV? Definition: No. If sen data exist, they are considered.
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Term: Does a TLV with a SEN notation protect already sensitized workers? Definition: No. It is designed to protect individuals from being sensitized, but does not protect already sensitized individuals. Term: What is the significance of the skin notation? Definition: The potential significant contribution to the overall exposure by the cutaneous route, including mucous membranes and the eyes by contact with vapors, liquids, and solids. Term: Can over exposure occur following dermal contact with liquids and aerosols from chemicals with skin notation, even when airborne concentrations are below the TLV? Definition: Yes Term: Is a skin notation applied to chemicals that cause skin irritation? Definition: No. A skin notation is not applied to chemicals that cause irritant or corrosive effects in the absence of systemic toxicity.
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Term: What should be considered to assess the dermal contribution to the dose from a compound with a skin notation? Definition: Biological monitoring. The skin notation indicates that air sampling alone is insufficient to quantify exposure. Term: A1 carcinogen defined as... Definition: Known human based on epi data Term: A2 carcinogen defined as... Definition: Suspected human carcinogen. Human data not sufficient, or carcinogenic in animals by relevant doses, routes, sties, tissue type to humans.
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