AHD II Midterm - Dr. Benton

AHD II Midterm - Dr. Benton - Term Definition immunity...

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Term: immunity Definition: protection Term: nonspecific Definition: innate immunity Term: nonspecific/innate Definition: immunity that involves physiological barriers, chemical barriers, inflammation, fever, and phagocytosis Term: nonspecific/innate Definition: immediate immunity that treats all antigens the same Term: specific immunity Definition: adaptive response to a specific substance
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Term: antigen (Ag) Definition: any substance capable of eliciting an immune response Term: antibody (Ab) Definition: produced by the body in response to a specific antigen Term: specific immunity Definition: immunity at the cellular level Term: T cells Definition: responsible for cell-mediated immunity that will kill infected cells, cancer cells Term: B cells Definition: responsible for antibody-mediated (humoral) immunity that will kill pathogens before they invade cells
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Term: B cells Definition: cells that produce antibodies; takes time Term: active, natural immunity Definition: immunity as a result of sickness and recovery Term: active, artificial immunity Definition: immunity as a result of vaccinations Term: passive, natural immunity Definition: immunity as a result of maternal antibodies (colostrum) Term: passive, artificial immunity Definition: immunity as a result of donor antibodies purified and administered to the sick
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Term: passive immunity Definition: immunity that is immediate but short-acting Term: antibodies Definition: substances produced by the body's B cells which bind foreign substances the goal is to prevent further harm by the foreign invader Term: IgM IgG IgA IgE IgD Definition: five classes of immunoglobulin Term: IgM Definition: - biggest immunoglobulin - primary immune response - secreted by circulating B lymphocytes - mainly in vascular system - activated by vaccines
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Term: IgG Definition: - secondary immune response - longer lasting - largest quantitiy - produced by plasma cells - transplacental immunity Term: IgG Definition: the only immunoglobulin that can cross the placenta Term: IgA Definition: - mucosal immunity - plasma cells in saliva, tears, nasal/bronchial secretions, mucous (GI, respiratory, and urogenital tract) - quick, local immunity - ocular-nasal vaccines Term: IgE Definition: - allergic response in cooperation with mast cells - eosinophil chemotactic factor - in excess, can be allergy or anaphylaxis
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Term: swollen face, hives, itchy Definition: vaccine reaction in dogs Term: repeated bouts of vomiting Definition: vaccine reaction in cats Term: IgD Definition: - low levels in serum - sits on surface of lymphocyte (not free-floating) - B cell receptor - activation of B cell to either plasma cell or memory B cell Term: inactivated or killed Definition: vaccine type that only activated humoral immunity
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Term: adjuvant Definition: additive in killed vaccineto increase vaccine stability = increased immune response Term: safe stable no disease transmission Definition: advantages of inactivated or killed vaccine Term: multiple boosters adjuvant complications (allergy, fibrosarcoma risk) Definition: disadvantages of inactivated or killed vaccine Term: bacterin
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