Chapter 2 Principals of Drug Actions

Chapter 2 Principals of Drug Actions - Term Definition...

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Term: Agonist Definition: Chemical or drug that binds to a receptor and creates and effect on the body. Term: Antagonist Definition: Chemical or drug that binds to a receptor but does not create an effect on the body, it blocks the receptor site from accepting an agonist. Term: Bioavailability Definition: Amount of drug that reaches the systemic circulation. Term: Drug administration Definition: Method by which a drug is made available to the body. Term: Enteral Definition: Use of the intestine.
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Term: First-pass effect Definition: Initial metabolism in the liver of a drug taken orally before the drug reaches the systemic circulation. Term: Hypersensitivity Definition: Allergic or immune mediated reaction to a drug, which can be serious, requiring airway maintenance or ventilatory assistance. Term: Idiosyncratic effect Definition: Abnormal or unexpected reaction to a drug, other than an allergic reaction, as compared with predicted effect.
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