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Chapter 4: Bleeding and transfusion

Chapter 4: Bleeding and transfusion - Term Definition 4...

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Term: 4 products of blood, what is in storage solution? what does plasma have? in which one do you find fibrinogen Definition: rbc, wbc, plasma, platelet CPD: citrate, phosphate, dextrose plasma : cryoprecipitate + specific clotting factor (fractor VII) cryo has fibrinogen and factor VIII Term: RBC: storage, age of packed RBC, are they still good at 6weeks? Definition: 6 weeks (42 days) 70% viable at 5 wks Term: platelet: pack volume, storage, age of , special treatment? concentrated or not? Definition: not sure, room temp, 5d, gentle agitation because it's concentrated Term: what is massive transfusion? extensive bleeding in massive transfusion, why? Definition: more than 10 units of RBC over 4-6hrs diluted coagulopathy, electrolyte derangement... Term: amount of rbc in one unit? total volume? effect on H&H? alkalosis or acidic? Definition: 200ml, 310mL, increase 1g/dL, 3% in a 70-kg person, acidic
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Term: pseudothrombocytopenia Definition: lab error, EDTA sensitive, can't count <40K , have to count manually Term: INR Definition: inter. normalized ratio, local thromboplastin use/int. , associated with Warfarin, normal =2-3 Term: question about bleeding history? Definition: bleeding after tooth extraction, prolonged periods, easily bruised, nosebleeds Term: most impt preop infor that predicts unexpected bleeding complication is not lab test but? Definition: past history of bleeding problem Term: impt med pertinent to bleeding? Definition: ASA, Plavix, Coumadin
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Term: hemostasis problem? Definition: thrombocytopenia, coag pathway and acquired coag inhibitor Term: how to measure bleeding time? what is the normal Definition: make wounds (6mmx1mm) x2; 5-10
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