Embryology

Embryology - Term Definition 2 molecules for PGC...

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Term: 2 molecules for PGC specification Definition: BMP4 - initiates expression of genes for specifying PGC. AND Blimp1 - stops cell from becoming somatic cell Term: The neural tube will form .... Definition: Brain and spinal cord Term: Neuralation Definition: Morphogenesis of neural plate to form neural tube Term: Neural induction Definition: Interaction between axial mesoderm and ectoderm. Ectoderm forms neural plate Term: Direction of neural plate formation Definition: Cranial to caudal
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Term: Cell type in neural plate Definition: Pseudo stratified columnar neuroepithelial cells Term: Days for formation of neural plate Definition: 17-22 Term: Day of start of neural folding (and location and direction) Definition: Starts on day 22 in the cervical level and goes in both cranial and caudal directions Term: Process of secondary neurulation Definition: Neural eminence cells first form solid neural cord, which then hollows out, and then connects to neural tube at week 8 Term: Neural tube closing Definition: Closes at first on day 22 at cervical level. Closes at Cranial level at day 24 and at Claudal level at day 26
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Term: Cells in the ventricular layer of the neural tube give rise to... Definition: Neurons, glial cells, ependymal cells Term: Cells in intermediate (mantle) layer of the neural tube give rise to .... Definition: Neural and glial cells have migrated here. It makes up the gray matter of spinal cord Term: Cells in marginal zone of neural tube give rise to... Definition: Neuron processes (axons and dendrites) and some glial cells. This is white matter Term: Meninges Definition: Cell layers of mesoderm and neural crest origin that cover spinal cord Term: Mitotically active zone in the neural tube Definition: The ventricular zone
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Term: Dorsal ventral patterning of spinal cord Definition: Sulcus limitans forms and divides spinal cord into the dorsal alar plates (dorsal horns) and the basal plates (ventral horn) Term: What connects the left and right alar plates? Definition: Thin roof plate Term: What connects the two basal plates? Definition: Floor plate Term: Motor component of spinal cord Definition: Basal plates- axons exit through the ventral roots Term: Sensory component of the spinal cord Definition: The alar plates. Sensory axons enter as dorsal roots and synapse with neurons in the dorsal horn
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Term: What things influence organization of sensory and motor function of spinal cord? Definition: Dorsal ectoderm induces dorsal cell types via BMP. Notochord induces floor plate and ventral cell types (motor neurons) via Shh Term: Spina Bifida Definition: Vertebral arch defect Term: Spina Bifida Occulta Definition: Usually just one vetebra doesn't form correctly. Just see tuft of hair. Term: Spina Bifida cystic Definition: The more severe forms of spina Bifida - meningocele, meningomyelocele, myeloschisis Term: Klippel-Feil Syndrome (Brevicollis) Definition: Fusion of two or more cervical vertebrae. Short neck and limited movement
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Term: Chordoma Definition: Remnants of notochord become malignant tumor Term: Somite patterning depends on...
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