3Unit+C+-+DNA.ppt - Deoxyribonucleic Acid(DNA DNA Deoxyribonucleic Acid is in every nucleus of almost every cell in the body It is the only known

3Unit+C+-+DNA.ppt - Deoxyribonucleic Acid(DNA DNA...

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Deoxyribonucleic Acid (DNA)
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DNA Deoxyribonucleic Acid is in every nucleus, of almost every cell in the body It is the only known molecule that can replicate itself
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DNA Functions to guide the repair of worn cells Helps to construct new cells (mitosis) using the original strand as a template If the DNA code changes, mutations may occur
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DNA = Chemical Heredity The genetic information that can be passed on from one generation to the next The information resides within chromosomes (genes)
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Chromosome Long thread of condensed genetic information In nucleus Composed of Proteins Nucleic Acids
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What do you remember about proteins?
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Proteins Made up of amino acids (20 different) Different organizations of amino acids = different proteins Altering a single amino acid forms a new protein
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Nucleic Acids Base unit is a nucleotide Arranged in long chains Made up of a phosphate group, a sugar molecule and a nitrogen base Adenine Guanine Cytosine Thymine
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Adenine
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Guanine
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Cytosine
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Thymine
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Nucleic Acids In DNA nitrogen bases always pair the same way Adenine – Thymine Cytosine – Guanine A – T C – G The DNA Game
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Purines Pyramidines
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DNA History and Creating the Structure
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Miesher Isolated DNA in 1869 Described it as a white slightly acidic chemical, but did not know its structure
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Rosalind Franklin Took an X-ray diffraction of DNA
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Watson and Crick Developed a 3 dimensional model of DNA in 1953 using the x-ray diffraction photo from Franklin In the April 25, 1953, issue of the science journal Nature, Watson and Crick wrote: ""We wish to suggest a structure for the salt of deoxyribose nucleic acid (DNA). This structure has novel features which are of considerable biological interest."
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