Cathy Boursiquot Week 7 Initial Discussion Pharmacotherapy for Hepatobiliary Disorders Advanced Pharmacology NURS- 6521N - 9 Review of Case Study: Patient HL comes into the clinic with the following symptoms: nausea, vomiting, and diarrhea. The patient has a history of drug abuse, and possible Hepatitis C. HL is currently taking the following prescription drugs: It is essential to complete a thorough health history and examination before diagnosing HL. There are several necessary questions related to HL’s medication list that should ask: • What is the prednisone prescribed for? • When were the last time drugs used or needles shared? • How long have the symptoms been present? • Describe the stools/emesis. • Synthroid 100 mcg daily • Nifedipine 30 mg daily • Prednisone 10 mg daily History of Present Illness and Medical History Patient presents with symptoms of diarrhea, nausea, and vomiting. Learning from HL’s medical history, HL appears to have some possible chronic conditions based on his current medications; Synthroid 100 mg daily, Nifedipine 30mg daily, and prednisone 10mg daily . Also, the history states that HL has a history of drug abuse and possible Hepatitis C that could have possibly started years ago or more recently.
Synthroid is a hormone replacement that is used to treat hypothyroidism, thyroid cancer and goiter (Drugs.com, 2017). Synthroid can have adverse effects if not taken correctly or if misused. Diarrhea is a common side effect of Synthroid, but nausea and vomiting along with appetite changes are a severe/adverse side effect of Synthroid and should be reported the health practitioner immediately (Drugs.com, 2017). In a healthy adult age 50 years or less with a weight of 70kg or more; it is recommended that the initial dose of 100-125 mcg/day be taken for a few months. In elderly patients, the starting dose should be the 25-50mcg day, and gradual increase or decrease of treatment may be needed. Thyroid should be checked every 6-8 weeks (Drugs.com, 2017). Also, care should be taken if the patient has any history of heart disease, coronary artery disease or blood clots. Assuming this patient is under 50 years old, the current dosage is appropriate; however lab workup is needed to verify if the TSH levels are within normal therapeutic levels. Nifedipine is a calcium channel blocker that is used to treat hypertension and chest pain (angina). The initial dose is 30-60mg orally once a day for the extended release and 10mg for the immediate release tablets. Vomiting, nausea, and diarrhea are not common side effects of this drug (Drugs.com, 2017). Nifedipine has also been linked to several instances of clinically apparent acute liver injury. Prednisone is a corticosteroid that prevents the release of substances in the body that causes inflammation it also suppresses the immune system (Drugs.com.2017). Prednisone treats many different conditions such as allergic disorders, skin
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- Summer '15
- Prednisone, Hepatitis C, HCV infection