08Chpt10watsolvita

08Chpt10watsolvita - THIAMIN • “Morale” vitamin •...

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1 THIAMIN • “Morale” vitamin • Destroyed by heat, oxidation, alkali, leaching, milling, toasting • Functions –coenzyme thiamin pyro- phosphate (TPP) in glycolysis , TCA cycle, & hexose/pentose pathway
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2 Deficiency – Beri beri (wet, dry) – Wernicke Korsakoff Syndrome (ataxia, psychosis, nystagmus) Symptoms: (possible in 7-10 days) – Loss of appetite, decreased muscle tone, depression, confusion, weakness, fatigue Metabolic marker : lactic acidosis “pitting edema”
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3 Thiamin RDA = 1.1-1.2 mg * based on 0.5 mg/1000kcal 1 lb watermelon = .4 mg sli ww bread = .12 mg 2 Tbsp sunflower seeds = .1 mg 1/2 c green peas = .23 mg 3 oz pork chop = .75 mg
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4 RIBOFLAVIN • Lost by leaching, by light and alkali; fairly stable to heat, acid and oxidation • Little storage; lost in urine
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5 Riboflavin Functions Coenzyme forms : FAD and FMN Electron transport–- ets, succinate dehydrogenase (TCA cycle), beta oxidation, Other RX : Synthesis/conversion of niacin,
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This note was uploaded on 03/20/2008 for the course HDF 304 taught by Professor Gray during the Spring '08 term at University of Texas.

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08Chpt10watsolvita - THIAMIN • “Morale” vitamin •...

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