UNIT 3-Module 8-Ch17,18 Vocab - Google Docs.pdf -...

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UNIT 3­Module 8­Ch17,18 Vocab Ch17: Immunological Disorders 1. antibody deficiency→ when few or no antibodies are produced (i.e selective IgA deficiency or agammaglobulinemia) 2. allergy→ a heightened immune response (hypersensitivity) to an allergen, especially of the IgE type 3. allergen→ an antigen that is usually a harmless environmental substance that cause an allergy 4. allografts → exchanges between genetically different individuals belonging to the same species, most human transplants 5. Arthus reaction→ a localized hypersensitivity response caused by immune complexes and neutrophils characterized by severe pain, swelling and redness. 6. asthma→ an immediate respiratory allergy 7. autoimmune disease→ produced as a result of an immune reaction against body’s own tissues 8. autograft → tissue transplanted from one site on an individual’s body to another site on his or her body 9. degranulation→ the release of mediators (i.e histamine) from a cell’s granules which cause: capillary dilation, smooth muscle contraction and increased mucus secretion 10. delayed­type hypersensitivity→ caused by cytokines released from sensitized T lymphocytes 11. desensitization (hyposensitization) → form of therapy for certain IgE mediated allergies that involves injecting extremely small but increasing amounts of antigen regularly over a period of months directing the response from IgE to IgG 12. DiGeorge syndrome→ when the thymus fails to develop in the embryo, so T cells do not differentiate and absent in circulation 13. disseminated intravascular coagulation (glomerulonephritis)→ devastating condition in which the clot forms in small blood vessels leading to failure of vital organs 14. Grave’s disease→ organ­specific autoimmune disease that affects the thyroid gland in which autoantibodies bind TSH receptor causing an overstimulation and enlargement (goiter) of the thyroid 1
UNIT 3­Module 8­Ch17,18 Vocab 15. Hay fever (allergic rhinitis) → marked by itching, teary eyes, sneezing and runny eyes 16. Hemolytic disease of the newborn (erythroblastosis fetalis) → occurs when a pregnant Rh­ women becomes sensitized (develop antibodies) to the Rh antigen during childbirth if she is carries a Rh+ baby. 17. Hives (urticaria) → skin condition characterized by wheal and flare 18. hypersensitivity→ a heightened immune response to an antigen that injures tissue 19. immunodeficiency→ disorder that occurs when the immune system is too weak to prevent infection or too weak to mount a response against an antigen 20. immunotherapy→ technique that alters the immune response and can therefore be

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