Microbiology - Spirochetes

Microbiology - Spirochetes - Term Definition What are the...

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Term: What are the characteristics of spirochetes? Definition: Spiral shaped bacteria, non-sporulating, and motile Term: What staining methods are available with spirochetes? Definition: Biological stains for Borrelia Silver impregnantion Darkfield microscopy Fluorescent microscopy Term: What are the modes of infection for Treponema pallidum subs. pallidum? Definition: Sexual contact - 1/3 of cases in gay population Congenitally acquired - one of the few organisms that can cross the placenta and affect the unborn child Blood transfusion - not a huge problem in US because all blood is screen serologically and it doesn't survive well in storage Direct inoculation - in individuals that are likely to interact with patients that have syphilis --> contact with chancres, mucosal contact through lesions
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Term: What are the virulence factors for Treponema pallidum? Definition: Outer membrane proteins - adherence to cells Hyaluronidase - invasion of tissue Fibronectin coating - makes it very difficult for antibodies to bind =
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  • Syphilis, Treponema pallidum, Leptospira, T. pallidum, Spirochaetes, Spirochaete

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