NucleicAcids - Nucleotide Structure Ribonucleic Acid Deoxyribonucleic Acid General structure of a nucleotide Which nucleic acid is this How do you

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Ribonucleic Acid Deoxyribonucleic Acid General structure of a nucleotide Which nucleic acid is this? How do you know? Nucleotide Structure Contrast with amino acid structure
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There are four types of bases in DNA and four in RNA Pyrimidines DNA contains A, C, G, and T RNA contains A, C, G, and U Cytosine Thymine Guanine Adenosine Uracil Purines Base Structures Amino acids: 20 side chains Nucleotides: only 4 bases
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RIBOSE DEOXYRIBOSE The difference in the sugars is the oxygen at the 2’ carbon The carbons in the sugar are numbered starting with the most oxidized. There are 5 carbons total. Can you see all of them? The 3’ and 5’ carbons are important for polymerization. Ribose Sugars
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Here is a three-dimensional representation of a nucleotide Can you find the phosphate, the sugar and the base?
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Nucleotide Tri-, Di, Mono- Phosphates Phosphates can be added and removed (energy storage) ATP, ADP, AMP refers to number of attached phosphates Only Nucleotide triphosphates can be added to a growing nucleic acid chain
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This note was uploaded on 03/21/2008 for the course BIO 2300 taught by Professor Brewer during the Spring '08 term at Georgia State University, Atlanta.

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NucleicAcids - Nucleotide Structure Ribonucleic Acid Deoxyribonucleic Acid General structure of a nucleotide Which nucleic acid is this How do you

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