CLAISEN CONDENSATION - the tetrahedral intermediate The...

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
CLAISEN CONDENSATION The first step involves adding a strong base to an ester to generate an enolate at the a carbon (note that the enolate has an additional resonance structure). The enolate can then add to another ester molecule by attacking the carbonyl to make
Background image of page 1
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: the tetrahedral intermediate. The carbonyl reforms with loss of the alcoxy group to make the b-keto ester. Example of a Claisen condensation: This is an example of an intramolecular Claisen reaction, called a Dieckmann condensation....
View Full Document

This note was uploaded on 03/21/2008 for the course CHEM 261 taught by Professor Austell during the Spring '08 term at UNC.

Ask a homework question - tutors are online