{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

E1 REACTION MECHANISM

E1 REACTION MECHANISM - make the double bond Example of an...

Info icon This preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
E1 REACTION MECHANISM: FIRST ORDER ELIMINATION - carbocation intermediate - RDS = formation of carbocation - 3° > 2° > 1° - weak base (strong base is not required) - likes heat! - rearrangement! B : = base X = leaving group (usually halide or tosylate) Steps: 1. The loss of the leaving group, which leaves in a very slow step, resulting in the formation of a carbocation 2. The base then attacks a neighboring hydrogen, forcing the electrons from the H–C bond to
Image of page 1
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: make the double bond. Example of an E1 reaction: Base Strength: A strong base not required, since it is not involved in the rate-determining step Leaving groups: A good leaving group is required, such as a halide or a tosylate, since it is involved in the rate-determining step. Rearangements: Since the mechanism goes through a carbocation intermediate, rearangements can occur....
View Full Document

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern