maoi.docx - MAOIs Drug Generic Name Isocarboxazid Drug...

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MAOIs Drug Generic Name: Isocarboxazid Drug Brand Name: Marplan Drug classifications: Antidepressant Drug Indication: Treatment of depression Drug dose range: PO (Adults): 10 mg twice daily; may be increased every 2 – 4 days by 10 mg, up to 40 mg/day by the end of the first wk, then may increase by up to 20 mg every wk, up to 60 mg/day in 2 – 4 divided doses. After optimal response is obtained, dose should be slowly decreased to lowest effective amount (40 mg/day or less). Dug-drug interactions: SRIS, SSNRIS, tricyclics, tetracyclics Therapeutic effects: Improve mood in depressed patients Drug antidote: Drug s/e: dizziness, h/a, blurred vision, nausea Drug a/e: hypertensive crisis Pt./Family teaching: Caution patient to avoid alcohol, CNS depressants, OTC drugs, and foods or beverages containing tyramine or excessive caffeine during and for at least 2 wk after therapy has been discontinued; they may precipitate a hypertensive crisis. Instruct patient to notify health care professional immediately if symptoms of hypertensive crisis (e.g. severe headache, palpitations, chest or
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  • Fall '17
  • y
  • Pharmacology, Antidepressant, hypertensive crisis, Monoamine Oxidase Inhibitor

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