Armanious, Matt-Module 10.pdf

Armanious, Matt-Module 10.pdf - Matthew Armanious Cell and...

Info icon This preview shows pages 1–2. Sign up to view the full content.

Matthew Armanious Cell and Tissue Engineering Homework-Module 10 1. The company Baxter received approval for its Fibrin Sealant (Tisseel®) in July, 2000 for application in surgical procedures. Features of this produce can be found at the website ( ). This material is being evaluated for a number of tissue engineering applications. Consider its use as a possible material in which to deliver tendon cells to a defect between bone and avulsed tendon. With regard to this prospective biomaterial application, please answer the following questions. Remember to give references when appropriate. a. What type of biomaterial is Tisseel® and what are its components? Tisseel is a fibrin sealant. Its components include a snap lock, easy spray system, duplospray system, doplotip applicator, and duplocath applicator. b. What reaction does Tisseel® undergo to form a sealant? Sealer protein and thrombin create soluble fibrinogen that, upon combining with thrombin, is transformed into fibrin. Tisseel undergoes the final step of the coagulation cascade to mimic a clot or sealant.
Image of page 1

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern