Unformatted text preview: EN 585.629 Cell and Tissue Engineering Module 04: Tissue Organization and Dynamics
Assignment Total Point Value = 30 Due by midnight on Day 7 of Module 4 This should be submitted to Blackboard as a pdf. 1. Name that tissue and structure! Assign every word from the word bank below to an image or structure within an image. Please use arrows and circles to point to the structure you are labeling when necessary. Note there are 2 bonus images. Correct identification of the structure/tissue is worth 1.5 bonus points each. Cilia Microvilli Skeletal muscle Columnar epithelium Liver sinusoid Myelin Neuron Simple squamous epithelium Stratified squamous epithelium Stratified cuboidal epithelium Elastin Cryptus Basement membrane EN 585.629 Cell and Tissue Engineering BONUS IMAGES EN 585.629 Cell and Tissue Engineering 2. Atherosclerosis (“hardening of the arteries”) is a disease hallmarked by the build-‐up of plaques in blood vessels. These plaques make it more difficult for blood to flow, which blocks the vital delivery of nutrients to downstream tissue. Complications from atherosclerosis include clots, heart attack and stroke. This disease can manifest in many locations including the coronary artery (when its termed “coronary artery disease”), the cerebral or peripheral vasculature. One way to treat extreme coronary artery disease is through surgery – a Coronary Artery Bypass Graft (CABG). In this surgery a healthy artery from elsewhere in the body is taken and use to bypass the segment of blocked vessel. The disease can become so progressed that it necessitates quadruple or even quintuple bypasses and typically the patients in this state do not have enough healthy vessels to sacrifice (see image where purple vessels indicate typical locations of bypass for the red coronary arteries). A. What is the most common alternative vessel used when there are no arteries left for CABG? B. What are the problems with this solution? What properties of this vessel are unmatched to the needed function? Please describe differences in both form and function. C. Why does this not end up being a problem for many patients in the long run? D. Describe 3 desirable design properties of tissue engineered blood vessels. Reference for image: Assignment Rubric Question Component Total Point Value 1 1pt each 13 2 A 5 B 4 C 4 D 4 Total Point Value = 30 ...
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- Spring '18
- Coronary artery bypass surgery, coronary artery, bonus images, Stratified cuboidal epithelium, Tissue Organization and Dynamics