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Armanious, Matt-Module 8 Homework.pdf

# Armanious, Matt-Module 8 Homework.pdf - Matt Armanious Cell...

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Matt Armanious Cell and Tissue Engineering Module 8 Homework 1) The Hagen-Poiseuille equation describes flow through a cylindrical tube. We discussed this in the context of blood flow but it is also applicable to respiration where air flows through cylindrical alveoli. Please use this equation to explain why breathing is so difficult for someone suffering from just mild asthma. Using the Hagen-Poiseuille equation, the key element when discussing asthma is airway resistance. Depending on the airway radius (R in this equation), the resistance will be affected. For asthma patience, the alveoli will constrict causing the radius to decrease, this will inevitably increase the resistance of air flow. Because flow is proportional to radius and inversely proportional to resistance, a decrease in radius and an increase in resistance will greatly decrease the flow (Q) of air, making it more difficult to breathe. 2) Derive the ordinary differential equation for the Kelvin viscoelastic solid (pictured below). Show all of your work (each step!) for full credit.

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3) In lecture we discussed the biomechanics of articular cartilage and how important it is for
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• Spring '18
• Drummond
• cell biology, Cellular differentiation, compressive load test

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