Homework help chapter 2 - Theories on aging and cell aging...

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Theories on aging and cell aging questions 1. Explain the following intrinsic theories of aging and how it may explain the loss of vitality of the cell a. genetics – change from early to late life Aging is a process that involves both genetics and environment, making it a multifactorial process. Genetics dictates the variance among individuals and their lifespan. The accumulation of molecular errors is what influences variations. b. mutation - explain impact on cell vitality Within certain genes when mutations occur they confer great stress resistance. This reduces the rate of cell damage and increases vitality. c. Telomeres – how does it explain P<D on the down slope of the aging curve Telomeres stabilize chromosomes. They are DNA proteins that cover the ends of linear DNA. After repeated mitotic divisions, telomeres become incredibly short and stop being able to divide further. This makes cells more susceptible to an increase in mutations as well as apoptosis and even death. d. Entropy – why may be the one theory that explains all other theories Entropy explains how it takes more than one thing working to create a whole. For aging telomeres, genetics, environment and mutation all play a hand. As over time maintenance decreases it makes us more susceptible to mutations and destruction increasing dysfunction.
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