tut 7.pdf - Name Tutorial TA Name MBB231 Spring 2018...

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Name_______________________________________ Tutorial & TA Name___________________________ MBB231 Spring 2018 Tutorial Questions Week of March 5 th 1) What would be the effect of mutating the KDEL sequence of a resident ER protein like BiP? Would this effect be similar or different from that of mutating the KDEL receptor protein? 2) How is it that a single nuclear pore complex can efficiently and bidirectionally transport proteins that possess different kinds of nuclear localization signals, e.g., import signal v. export signal? 3) Why do mitochondria need a special translocator to import proteins across the outer membrane when the membrane already has large pores formed by porins? In your answer explain the difference
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