Discussion Week 5 .pdf - BIMM 120 Week 5 Discussion Lecture...

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BIMM 120 Week 5 Discussion
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113JeJHcturJe " Mobile genetic elements and Horizontal gene transfer 2
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,**volutNion oKf LgJenomJes Vertical inheritance × Evolutionary history × duplications/deletions Horizontal transfer × Genes are from other organisms 3
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0omologs : genes with shared evolutionary ancestry 7rthologs : homologs in multiple genomes that are functionally equivalent 8IrIlogs : homologs that are similar but may be functionally divergent due to gene duplication 4
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How? × Transformation × Transduction × Conjugation 5 ,,JenJetNiJHc JexJHcMhHFanLgJe Using what? × Plasmids × Insertion sequences × Transposons × Bacteriophage
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--/omoloLgous 7797JeJHcomIGbNinHFatNion × Donor and recipient sequences are highly similar × Example: RecA-mediated recombination × RecBCD involved in process of endonucleases making nicks in donor DNA × RecA mediates strand stabilization and catalyzes pairing of ssDNA with complementary dsDNA 6
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99;9rHFansKformHFatNion × Uptake and incorporation of free external DNA ×
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