{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

MALARIA.pptx - MALARIA Plasmodium 1 P vivax = benign...

Info icon This preview shows pages 1–9. Sign up to view the full content.

View Full Document Right Arrow Icon
MALARIA
Image of page 1

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Plasmodium 1. P. vivax = benign tertian malaria 2. P. falciparum = aestivoautumnal malignant tertian or subtertian malaria 3. P. malariae = quartan malariae 4. P. ovale
Image of page 2
LIFE CYCLE 1. Schizogony - the asexual method of reproduction; occurs in intermediate host (MAN) 2. Sporogony - the sexual method of reproduction; occurs in definitive host (MOSQUITO)
Image of page 3

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
HUMAN CYCLE * SPOROZOITES: infective form of the parasite found in the salivary glands of the female ANOPHELES MOSQUITO (definitive host) * Man gets infection by the bite of an infected ____ mosquito. During the act of biting the proboscis of the mosquito pierces the skin & saliva containing ____ is infected directly into the blood stream
Image of page 4
HUMAN CYCLE * The cycle in man comprises of the following stages: Primary exoerythrocytic schizogony Erythrocyctic schizogony Gametogony Secondary exoerythrocytic schizogony
Image of page 5

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
1. Primary exoerythrocyctic schizogony Within 1 hour all the sporozoites leave the blood stream & enter into the liver parenchyma cells (spindle-shaped bodies become rounded) They undergo a process of multiple nuclear division, followed by cytoplasmic division & develop into primart exoerythrocytic schizont The duration of the cycle varies. P. falciparum - 6 days P. vivax - 8 days P. ovale - 9 days P. malariae - 13 to 16 days When primary shizogony is complete, the liver cell ruptures & releases merozoites into the blood stream
Image of page 6
2. Erythrocytic schizogony Merozoites enter the blood stream and invade RBCs where they multiply at the expense of the host cells Passes thru the stages of trophozoites, schizonts & merozoites & followed by cytoplasmic division, & RBCs rupture to release the individual merozoites which then infect fresh RBCs The parasitic multiplication during this phase is responsible for bringing on a clinical attack of malaria
Image of page 7

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
3. Gametogony After malarial parasites have undergone erythrocytic schizogony for certain period, some merozoites develop within red cells into male & female gametocytes known as MICROGAMETOCYTES & MACROGAMETOCYTES respectively. Only mature gametocytes are found in the peripheral blood.
Image of page 8
Image of page 9
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern