A_Introduction.pdf - Practical Applications Biochemistry...

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1/9/2018 1 Biochemistry BCHE 5180/6180 Evert C. Duin 1 “Dr. Duin, I am a pre - med student. Why do I have to know all this stuff?” 2 How can we use our knowledge of proteins, enzymes and metabolic pathways to benefit human kind and be good stewards of this planet? 1. Taxol 2. Insuline Pacific yew tree ( Taxus brevifolia ) Practical Applications 3 Example 1 Taxol (paclitaxel) , found in the bark of the Pacific yew tree, is a widely used anti-cancer drug It takes 30,000 pounds of bark (2,000-4,000 trees) to produce one kilogram of taxol. The tree has to be sacrificed to produce the bark It can take decades for the Pacific yew to reach shoulder height, small trees yield less bark. 4
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