2018Lecture 8 (2-5-18).pdf

2018Lecture 8 (2-5-18).pdf - Stem Cells Nuclear...

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Figure 8-2C Nuclear reprogramming by Egg Cytoplasm Stem Cells Figure 8-18 Nuclear reprogramming induced by four genes (proteins) (Induced pluripotent stem [iPS] cells) Are genetic clones IDENTICAL to the DONOR? i) Foster Environment (not SAME mother) ii) Other environmental factors (diet, pollution, stress) Effect of Environment on Gene Expression NO! Chapter 8 Control of Gene Expression 1. Cells express different sets of genes 2. House-keeping genes 3. Genes and environment Chapter 8 Control of Gene Expression 1. Cells express different sets of genes 2. House-keeping genes 3. Genes and environment 4. Levels of Gene Regulation Flow of Genetic Information DNA (Genotype) mRNA Protein Function (Phenotype) Several ways to regulate flow of information (i.e., regulate gene expression) Figure 8-3
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Figure 8-12: Many Transcription factors to regulate One gene Multiple transcription regulators enable the integration of several conditions Regulating multiple genes in response to one condition Figure 8-15: One
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  • Spring '13
  • Staff
  • cell biology, DNA, gene silencing, House-keeping genes, differentiated cells types

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